Dual Role of Alkynyl Halides in One-Step Synthesis of Alkynyl Epoxides
Alexander Trofimov, Natalia Chernyak and Vladimir Gevorgyan*
*Department of Chemistry, University of Illinois at Chicago,
845 West Taylor Street, Chicago, Illinois 60607-7061, Email: vlad
uic.edu
A. Trofimov, N. Chernyak, V. Gevorgyan, J. Am. Chem. Soc., 2008, 130, 13538-13539.
DOI: 10.1021/ja806178r
Abstract
Alkynyl halides serve as a source of Br+ and acetylide ions in an efficient one-step preparation of alkynyl epoxides, important organic building blocks, from readily available starting materials.
see article for more examples
proposed mechanism
Key Words
ID: J48-Y2008-2790
