A Phosphine-Catalyzed [3 + 2] Annulation Reaction of Modified Allylic Compounds and N-Tosylimines
Suqing Zheng and Xiyan Lu*
*State Key Laboratory of Organometallic Chemistry, Shanghai
Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu,
Shanghai, 200032, China, Email: xylu
mail.sioc.ac.cn
S. Zheng, X. Lu, Org. Lett., 2008, 10, 4481-4484.
DOI: 10.1021/ol801661y
see article for more reactions
Abstract
A phosphine-catalyzed annulation of modified allylic ylides with various aromatic imines gives 3-pyrrolines in moderate to very good yield. The presence of a substituent (R) in the allylic compound is crucial for this reaction.
see article for more examples
proposed mechanism
Key Words
ID: J54-Y2008-2900
