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Deoxygenation of Pyridine N-Oxides by Palladium-Catalysed Transfer Oxidation of Trialkylamines

José A. Fuentes, Matthew L. Clarke*

*School of Chemistry, University of St Andrews, EaSTCHEM, St Andrews, Fife, KY16 9ST, UK, Email:

J. A. Fuentes, M. L. Clarke, Synlett, 2008, 2579-2582.

DOI: 10.1055/s-0028-1083508


A convenient and chemoselective method for deoxygenation of pyridine N-oxide derivatives by transfer oxidation of triethylamine under microwave irradiation is catalysed by [Pd(OAc)2]/dppf.

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Key Words

deoxygenation, homogeneous catalysis, palladium, pyridine N-oxides, ligand effects, microwave synthesis

ID: J60-Y2008-2950