Organic Chemistry Portal



Asymmetric Pauson-Khand-type Reaction Mediated by Rh(I) Catalyst at Ambient Temperature

Dong Eun Kim, In Su Kim, Virginie Ratovelomanana-Vidal, Jean-Pierre GenÍt and Nakcheol Jeong*

*Department of Chemistry, Korea University, Seoul, 136-701, Korea, Email:

D. E. Kim, I. S. Kim, V. Ratovelomanana-Vidal, J.-P. GenÍt, N. Jeong, J. Org. Chem., 2008, 73, 7985-7989.

DOI: 10.1021/jo801236c


An efficient asymmetric PKR is mediated by a Rh(I) catalyst bearing a (R)-3,5-diMeC4H4-BINAP ligand at ambient temperature under a reduced partial pressure of CO (0.1 atm). PKR products are provided in high chemical yield as well as high enantioselectivity.

see article for more examples

Key Words

Pauson-Khand Reaction

ID: J42-Y2008-2990