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Nickel-Catalyzed Reductive Carboxylation of Styrenes Using CO2

Catherine M. Williams, Jeffrey B. Johnson and Tomislav Rovis*

*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, Email:

C. M. Williams, J. B. Johnson, T. Rovis, J. Am. Chem. Soc., 2008, 130, 14936-14937.

DOI: 10.1021/ja8062925


A nickel-catalyzed reductive carboxylation of styrenes using CO2 proceeds under mild conditions using diethylzinc as the reductant. The catalyst system is very robust and will fixate CO2 in good yield even if exposed to only an equimolar amount introduced into the headspace above the reaction.

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Key Words

Hydrocarboxylation, Benzylation

ID: J48-Y2008-3310