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Manganese-Catalyzed Cross-Coupling Reaction between Aryl Grignard Reagents and Alkenyl Halides

Gérard Cahiez*, Olivier Gager and Fabien Lecomte

*Department of Chemistry, CNRS - Universit de Paris13, 74, Rue Marcel Cachin, F-93017 Bobigny, France, Email:

G. Cahiez, O. Gager, F. Lecomte, Org. Lett., 2008, 10, 5255-5256.

DOI: 10.1021/ol802273e (free Supporting Information)


Aryl Grignard reagents react stereospecifically with alkenyl halides in the presence of manganese chloride as catalyst to afford cross-coupled products in good yields.

see article for more examples

A New Efficient Catalytic System for the Chemoselective Cobalt-Catalyzed Cross-Coupling of Aryl Grignard Reagents with Primary and Secondary Alkyl Bromides

G. Cahiez, C. Chaboche, C. Duplais, A. Moyeux, Org. Lett., 2009, 11, 277-280.

Key Words


ID: J54-Y2008-3530