Broadly Applicable Synthesis of 1,2,4,5-Tetraoxanes
Prasanta Ghorai and Patrick H. Dussault*
*Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, Email: pdussault1unl.edu
P. Ghorai, P. H. Dussault, Org. Lett., 2009, 11, 213-216.
Re2O7 is a mild and efficient catalyst for the high-yielding condensation of 1,1-dihydroperoxides with ketones or aldehydes to form 1,2,4,5-tetraoxanes. When applied in tandem with a Re(VII)-catalyzed synthesis of 1,1-dihydroperoxides, the reaction provides a high-yielding one-pot conversion of ketones or aldehydes to tetraoxanes.
see article for more examples
see article for more reactions
P. Ghorai, P. H. Dussault, Org. Lett., 2008, 10, 4577-4579.