Palladium-Indolylphosphine-Catalyzed Hiyama Cross-Coupling of Aryl Mesylates
Chau Ming So, Hang Wai Lee, Chak Po Lau and Fuk Yee Kwong*
*Department of Applied Biology and Chemical Technology, The
Hong Kong Polytechnic University, Kowloon, Hong Kong, Email: bcfyk
inet.polyu.edu.hk
C. M. So, H. W. Lee, C. P. Lau, F. Y. Kwong, Org. Lett., 2009, 11, 317-320.
DOI: 10.1021/ol802493z
Abstract
Aryl mesylates are found to be applicable as electrophiles in organosilicon-mediated coupling reactions. The catalyst system comprising Pd(OAc)2 and CM-phos as ligand is highly effective in catalyzing Hiyama cross-coupling of various aryl and heteroaryl mesylates. The presence of acetic acid efficiently suppresses the mesylate decomposition.
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C. M. So, C. P. Lau, A. S. C. Chan, F. Y. Kwong, J. Org. Chem., 2008, 73, 7731-7734.
C. M. So, C. P. Lau, A. S. C. Chan, F. Y. Kwong, J. Org. Chem., 2008, 73, 7731-7734.
Key Words
ID: J54-Y2009-0210
