Molybdenum(VI) Dichloride Dioxide Catalyzed Conversion of β-Hydroxycarbonyls into α-Bromo 1,3-Dicarbonyls by N-Bromosuccinimide
Kandasamy Jeyakumar, Dillip Kumar Chand*
*Department of Chemistry, Indian Institute of Technology Madras, Chennai 600 036, India, Email: dillipiitm.ac.in
K. Jeyakumar, D. K. Chand, Synthesis, 2009, 306-310.
An efficient one-pot transformation of β-hydroxycarbonyl compounds to α-brominated 1,3-dicarbonyl compounds is achieved with MoO2Cl2 in the presence of N-bromosuccinimide. All the reactions were carried out under mild conditions and provide good yields. No bromination occurs at benzylic and allylic positions.
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