LiOAc-Catalyzed Chemoselective Deprotection of Aryl Silyl Ethers under Mild Conditions
Bing Wang*, Hui-Xia Sun and Zhi-Hua Sun
*Department of Chemistry, Fudan University, 220 Handan Road,
Shanghai 200433, China, Email: wangbing
fudan.edu.cn
B. Wang, H.-X. Sun, Z.-H. Sun, J. Org. Chem., 2009, 74, 1781-1784.
DOI: 10.1021/jo802472s
Abstract
An efficient and chemoselective protocol using LiOAc as a bifunctional Lewis acid-Lewis base catalyst allows the selective deprotection of aryl silyl ethers in the presence of acetates, epoxides, and aliphatic silyl ethers.
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proposed mechanism
Key Words
TBDMS-Ethers, TBDPS-Ethers
ID: J42-Y2009-0620
