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Facile Synthesis of Highly Stable Gold Nanoparticles and Their Unexpected Excellent Catalytic Activity for Suzuki-Miyaura Cross-Coupling Reaction in Water

Jie Han, Yan Liu and Rong Guo*

*School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, Jiangsu, P. R. China, Email:

J. Han, Y. Liu, R. Guo, J. Am. Chem. Soc., 2009, 131, 2060-2061.

DOI: 10.1021/ja808935n


Poly(2-aminothiophenol)-stablized gold nanoparticles with proper gold size and polymer thickness are active catalysts for Suzuki-Miyaura cross-coupling reaction of aryl halides with arylboronic acids in water and air. High yields can be obtained with aryl halides or arylboronic acids bearing various substituents. The catalyst can be recycled.

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Key Words

Suzuki Coupling, Biaryls, Green Chemistry

ID: J48-Y2009-0670