Efficient Enantioselective Reduction of Ketones with Daucus carota Root
J. S. Yadav,* S. Nanda, P. Thirupathi Reddy and A. Bhaskar Rao
*Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India, Email: yadavpubiict.res.in
J. S. Yadav, S. Nanda, P. T. Reddy, A. Bhaskar, Rao, J. Org. Chem., 2002, 67, 3900-3903.
DOI: 10.1021/jo010399p (free Supporting Information)
An efficient reduction of various prochiral ketones such as acetopehones, α-azido aryl ketones, β-ketoesters, and aliphatic acyclic and cyclic ketones to the corresponding optically acive secondary alcohols with good chemical yield was achieved by using Daucus carota, root plant cells under extremely mild and environmentally benign conditions in aqueous medium.
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