Synthesis of 3,4-Disubstituted Maleimides by Selective Cross-Coupling Reactions Using Indium Organometallics
Latifa Bouissane, José Pérez Sestelo* and Luis A. Sarandeses*
*Departamento de Química Fundamental, Universidade da Coruña,
E-15071 A Coruña, Spain, Email: sestelo
udc.es, qfsarandudc.es
L. Bouissane, J. P. Sestelo, L. A. Sarandeses, Org. Lett., 2009, 11, 1285-1288.
DOI: 10.1021/ol900063p
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Abstract
Unsymmetrical 3,4-disubstituted maleimides have been synthesized by palladium-catalyzed cross-coupling reactions of indium organometallics with 3,4-dihalomaleimides.Various alkyl, aryl, heteroaryl, and alkynyl 3,4-disubstituted maleimides have been prepared in good yields and with high selectivity.
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Key Words
ID: J54-Y2009-0840
