Direct Asymmetric Benzoyloxylation of Aldehydes Catalyzed by 2-Tritylpyrrolidine
Taichi Kano, Haruka Mii and Keiji Maruoka*
*Department of Chemistry, Graduate School of Science, Kyoto
University, Sakyo, Kyoto 606-8502, Japan, Email: maruoka
kuchem.kyoto-u.ac.jp
T. Kano, H. Mii, K. Maruoka, J. Am. Chem. Soc., 2009, 131, 3450-3451.
DOI: 10.1021/ja809963s
Abstract
A direct asymmetric benzoyloxylation of aldehydes with benzoyl peroxide catalyzed by (S)-2-(triphenylmethyl)pyrrolidine provides optically active α-benzoyloxyaldehydes as useful chiral building blocks.
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Key Words
α-hydroxylation, benzoyl peroxide, organocatalysis
ID: J48-Y2009-0890
