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Intramolecular Hydroamination of Unactivated Alkenes with Secondary Alkyl- and Arylamines Employing [Ir(COD)Cl]2 as a Catalyst Precursor

Kevin D. Hesp and Mark Stradiotto*

*Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J3, Email: mark.stradiottodal.ca

K. D. Hesp, M. Stradiotto, Org. Lett., 2009, 11, 1449-1452.

DOI: 10.1021/ol900174f (free Supporting Information)


Abstract

[Ir(COD)Cl]2 is an effective precatalyst for the intramolecular hydroamination of a range of unactivated alkenes with pendant secondary amines. The catalyst can be used at relatively low loadings and without the need for added ligands or other cocatalysts.


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Key Words

pyrrolidines


ID: J54-Y2009-0960