Intramolecular Hydroamination of Unactivated Alkenes with Secondary Alkyl- and Arylamines Employing [Ir(COD)Cl]2 as a Catalyst Precursor
Kevin D. Hesp and Mark Stradiotto*
*Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J3, Email: mark.stradiottodal.ca
K. D. Hesp, M. Stradiotto, Org. Lett., 2009, 11, 1449-1452.
DOI: 10.1021/ol900174f (free Supporting Information)
[Ir(COD)Cl]2 is an effective precatalyst for the intramolecular hydroamination of a range of unactivated alkenes with pendant secondary amines. The catalyst can be used at relatively low loadings and without the need for added ligands or other cocatalysts.
see article for more examples