Deprotection of Homoallyl (hAllyl) Derivatives of Phenols, Alcohols, Acids, and Amines
Bruce H. Lipshutz*, Subir Ghorai and Wendy Wen Yi Leong
*Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, Email: lipshutzchem.ucsb.edu
B. H. Lipshutz, S. Ghorai, W. W. Y. Leong, J. Org. Chem., 2009, 74, 2854-2857.
see article for more reactions
The homoallyl moiety (hAllyl) can be used as a general protecting group for several functionalities. It can be chemoselectively removed via a sequential, one-pot cross-metathesis/elimination sequence.
see article for more examples
Deprotection (Ethers, Amines, Carboxylic Esters), Cross Metathesis