Deprotection of Homoallyl (^hAllyl) Derivatives of Phenols, Alcohols, Acids, and Amines

Bruce H. Lipshutz*, Subir Ghorai and Wendy Wen Yi Leong

*Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, Email: lipshutzchem.ucsb.edu

B. H. Lipshutz, S. Ghorai, W. W. Y. Leong, J. Org. Chem., 2009, 74, 2854-2857.

DOI: 10.1021/jo900012z

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Abstract

The homoallyl moiety (hAllyl) can be used as a general protecting group for several functionalities. It can be chemoselectively removed via a sequential, one-pot cross-metathesis/elimination sequence.

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Key Words

Deprotection (Ethers, Amines, Carboxylic Esters), Cross Metathesis

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ID: J42-Y2009-1040