A Facile Mild Deprotection Protocol for 1,3-Dithianes and 1,3-Dithiolanes with 30% Hydrogen Peroxide and Iodine Catalyst in Aqueous Micellar System
Nemai C. Ganguly*, Sujoy Kumar Barik
*Department of Chemistry, University of Kalyani, Kalyani
741235, WB, India, Email:
nemai_g
yahoo.co.in
N. G. Ganguly, S. K. Barik, Synthesis, 2009, 1393-1399.
Abstract
A simple protocol for the deprotection of 1,3-dithianes and 1,3-dithiolanes showed tolerance for a number of phenol and amino protecting groups using 30% aqueous hydrogen peroxide activated by iodine catalyst (5 mol%) in water in the presence of sodium dodecyl sulfate (SDS) under essentially neutral conditions without any detectable overoxidation.
see article for more examples
Key Words
1,3-dithianes, 1,3-dithiolanes, iodine, 30% hydrogen peroxide, sodium dodecyl sulfate (SDS)
ID: J66-Y2009-1300
