Copper-Catalyzed Aerobic Oxidative Coupling of Terminal Alkynes with H-Phosphonates Leading to Alkynylphosphonates

Yuxing Gao, Gang Wang, Lu Chen, Pengxiang Xu, Yufen Zhao, Yongbo Zhou and Li-Biao Han*

*National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8565, Japan, Email: libiao-hanaist.go.jp

Y. Gao, G. Wang, L. Chen, P. Xu, Y. Zhao, Y. Zhou, L.-B. Han, J. Am. Chem. Soc., 2009, 131, 7956-7957.

DOI: 10.1021/ja9023397

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Abstract

Copper-catalyzed aerobic oxidative coupling of terminal alkynes with H-phosphonates affords alkynylphosphonates in high yields.

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Silver-Free Direct Synthesis of Alkynylphosphine Oxides via spC-H/P(O)-H Dehydrogenative Coupling Catalyzed by Palladium

J.-Q. Zhang, T. Chen, J.-S. Zhang, L.-B. Han, Org. Lett., 2017, 19, 4692-4695.

Rhodium-Catalyzed Regio- and Stereoselective Addition of Diphenylphosphine Oxide to Alkynes

L.-B. Han, C.-Q. Zhao, M. Tanaka, J. Org. Chem., 2001, 66, 5929-5932.

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Key Words

phosphonates, oxygen

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ID: J48-Y2009-1770