Organic Chemistry Portal

Abstracts

Search:

Iron-Catalyzed Amidation of Alkynyl Bromides: A Facile Route for the Preparation of Ynamides

Bangben Yao, Zunjun Liang, Tianmin Niu and Yuhong Zhang*

*Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China, Email: yhzhangzju.edu.cn

B. Yao, Z. Liang, T. Niu, Y. Zhang, J. Org. Chem., 2009, 74, 4630-4633.

DOI: 10.1021/jo900595c


Abstract

A facile route to ynamides in high yields was achieved through an iron-catalyzed C-N coupling reaction of amides with alkynyl bromides in the presence of 20 mol % of N,N′-dimethylethane-1,2-diamine (DMEDA).

see article for more examples



Key Words

sulfonamides, amides, carbamates, alkynyl bromides


ID: J42-Y2009-1830