Facile Ring-Opening of Oxiranes by H2O2 Catalyzed by Phosphomolybdic Acid
Yun Li, Hong-Dong Hao and Yikang Wu*
*State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China, Email: yikangwumail.sioc.ac.cn
Y. Li, H.-D. Hao, Y. Wu, Org. Lett., 2009, 11, 2691-2694.
DOI: 10.1021/ol900811m (free Supporting Information)
In the presence of catalytic amounts of phosphomolybdic acid (PMA), ethereal hydrogen peroxide reacted readily with a range of epoxides at ambient temperature, giving corresponding β-hydroxyhydroperoxides in good yields.
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Y. Li, H.-D. Hao, Q. Zhang, Y. Wu, Org. Lett., 2009, 11, 1615-1618.