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Solvent-Free Microwave-Assisted Suzuki-Miyaura Coupling Catalyzed by PEPPSI-iPr

Pierrick Nun, Jean Martinez, Frédéric Lamaty*

*Institut des Biomolécules Max Mousseron UMR 5247, CNRS, Université Montpellier 1 et Université Montpellier 2, Place Eugène Bataillon, 34095 Montpellier Cedex 05, France, Email:

P. Nun, J. Martinez, F. Lamaty, Synlett, 2009, 1761-1764.

DOI: 10.1055/s-0029-1217359


Microwave activation enables a Suzuki coupling of boronic acids with aryl halides under solvent-free conditions using the NHC-stabilized palladium catalyst PEPPSI-iPr.

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Key Words

Suzuki reaction, N-heterocyclic carbene catalyst, biaryls, green chemistry, cross-coupling

ID: J60-Y2009-1980