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Solvent-Free Synthesis of Alkylthiazolium-Based Ionic Liquids and their Use as Catalysts in the Intramolecular Stetter Reaction

Audrey Aupoix, Giang Vo-Thanh*

*Laboratoire de Catalyse Moléculaire, Institut de Chimie Moléculaire et des Matériaux d'Orsay, UMR 8182, Université Paris-Sud 11, 91405 Orsay Cedex, France, Email:

A. Aupoix, G. Vo-Thanh, Synlett, 2009, 1915-1920.

DOI: 10.1055/s-0029-1217518

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Alkylthiazolium-based ionic liquids, which can be synthesized under green conditions, and triethylamine have been found to catalyze efficiently the intramolecular Stetter reaction, giving excellent yields within very short reaction times using solvent-free microwave activation conditions.

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Key Words

Stetter Reaction, Organocatalysis, Microwave Synthesis, Green Chemistry

ID: J60-Y2009-2020