An Efficient Oxidative Conversion of Aldehydes into 2-Substituted 2-Oxazolines Using 1,3-Diiodo-5,5-dimethylhydantoin
Shogo Takahashi, Hideo Togo*
*Graduate School of Science, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba 263-8522, Japan, Email: togofaculty.chiba-u.jp
S. Takahashi, H. Togo, Synthesis, 2009, 2329-2332.
Various aromatic and aliphatic aldehydes were converted into the corresponding 2-aryl and 2-alkyl-2-oxazolines, respectively, in good yields by reaction with 2-aminoethanol and 1,3-diiodo-5,5-dimethylhydantoin.
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2-aryl-2-oxazoline, 2-alkyl-2-oxazoline, 2-oxazolines, 1,3-diiodo-5,5-dimethylhydantoin, aldehydes, 2-aminoethanol, chiral oxazoline