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An Efficient Method for Chemoselective Thioacetalization of Aldehydes in the Presence of a Catalytic Amount of Acidic Ionic Liquid under Solvent-Free Conditions

Abdol Reza Hajipour*, Ghobad Azizi, Arnold E. Ruoho

*Department of Pharmacology, University of Wisconsin Med. Sch., 1300 University Avenue, Madison, WI 53706-1532, USA, Email:

A. R. Hajipour, G. Azizi, A. E. Ruoho, Synlett, 2009, 1974-1978.

DOI: 10.1055/s-0029-1217550


A catalytic amount of a water-stable Brønsted acidic ionic liquid with an alkane sulfonic acid catalyzed a mild and chemoselective thioacetalization of various aldehydes to afford 1,3-dithianes in very good yield and short reaction times.

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Key Words

acid catalysis, thioacetalization, Brønsted acidic ionic liquid

ID: J60-Y2009-2120