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Gold(III) Bromide Catalyzed Furannulation of 2-Alkynylcycloalk-2-enols: An Expedient Route to Fused Furans

C. Praveen, P. Kiruthiga, P. T. Perumal*

*Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai 600020, India, Email:

C. Praveen, P. Kiruthiga, P. T. Perumal, Synlett, 2009, 1990-1996.

DOI: 10.1055/s-0029-1217517


An efficient synthesis of structurally diverse fused furans in good yields from 2-alkynyl­cycloalk-2-enols via gold(III) bromide catalyzed cycloisomerization was achieved under moderate reaction conditions.

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Key Words

Sonogashira Coupling, enynes, 2-alkynylcycloalk-2-enol, gold(III), cycloisomerization, furans

ID: J60-Y2009-2150