MgI2-accelerated enantioselective Morita-Baylis-Hillman reactions of cyclopentenone utilizing a chiral DMAP catalyst
Alejandro Bugarin and Brian T. Connell*
*Department of Chemistry, Texas A&M University, P.O. Box
30012, College Station, Texas 77842-3012, Email: connellmail.chem.tamu.edu
A. Bugarin, B. T. Connell, Chem. Commun., 2010, 46, 2644-2646.
DOI: 10.1039/c001977a
Abstract
A planar chiral DMAP catalyst efficiently promotes asymmetric Morita-Baylis-Hillman reactions of cyclopentenone with various aldehydes in the presence of MgI2 as cocatalyst.
see article for more examples
Acceleration of the Morita-Baylis-Hillman Reaction by a Simple Mixed Catalyst System
A. Bugarin, B. T. Connell, J. Org. Chem., 2009, 74, 4638-4641.
Key Words
Baylis-Hillman Reaction, Cyclopentenones
ID: JXX-Y2010-0000