Nickel-Catalyzed Direct Conjugate Addition of Simple Alkenes to Enones
Sensuke Ogoshi*, Toshifumi Haba and Masato Ohashi
*Department of Applied Chemistry, Graduate School of
Engineering, Osaka University, Suita, Osaka 565-0871, Japan, Email: ogoshi
chem.eng.osaka-u.ac.jp
S. Ogoshi, T. Haba, M. Ohashi, J. Am. Chem. Soc., 2009, 131, 10350-10351.
DOI: 10.1021/ja903510u
Abstract
A direct conjugate addition of simple alkenes to enones has been achieved in the presence of a Ni(0)/PCy3 catalyst. This reaction is a straightforward method for the introduction of an alkenyl group at the β-position of enones.
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Key Words
Conjugate Addition, Alkenylation
ID: J48-Y2009-2220
