A Metal-Free General Procedure for Oxidation of Secondary Amines to Nitrones
Carolina Gella, Èric Ferrer, Ramon Alibés, Félíx Busqué, Pedro de March, Marta Figueredo and Josep Font
*Universitat Autònoma de Barcelona, Departament de Química,
08193 Bellaterra, Spain, Email: felix.busque
uab.es,
marta.figueredouab.es
C. Gella, È. Ferrer, R. Alibés, F. Busqué, P. de March, M. Figueredo, J. Font, J. Org. Chem., 2009, 74, 6365-6367.
DOI: 10.1021/jo901108u
Abstract
A general, efficient and metal-free protocol for the direct oxidation of secondary amines to nitrones tolerates other functional groups or existing stereogenic centers using Oxone in a biphasic basic medium as the sole oxidant.
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Key Words
ID: J42-Y2009-2560
