A Remarkably Simple One-Step Procedure for the Preparation of α-Bromo-α,β-Unsaturated Carbonyl Compounds
Divya Jyothi, S. HariPrasad*
*Department of Studies in Chemistry, Central College Campus, Bangalore University, Bangalore 560001, India, Email: hariprasadbub.ernet.in
D. Jyothi, S. HariPrasad, Synlett, 2009, 2309-2311.
DOI: 10.1055/s-0029-1217726 (free Supporting Information)
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A fast and convenient one-step procedure allows the conversion of α,β-unsaturated carbonyl compounds into their corresponding bromo-enones at room temperature under very mild conditions in high yields using NBS-Et3N • 3 HBr in the presence of potassium carbonate in dichloromethane.
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