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A Remarkably Simple One-Step Procedure for the Preparation of α-Bromo-α,β-Unsaturated Carbonyl Compounds

Divya Jyothi, S. HariPrasad*

*Department of Studies in Chemistry, Central College Campus, Bangalore University, Bangalore 560001, India, Email:

D. Jyothi, S. HariPrasad, Synlett, 2009, 2309-2311.

DOI: 10.1055/s-0029-1217726

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A fast and convenient one-step procedure allows the conversion of α,β-unsaturated carbonyl compounds into their corresponding bromo-enones at room temperature under very mild conditions in high yields using NBS-Et3N • 3 HBr in the presence of potassium carbonate in dichloromethane.

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Key Words

NBS-Et3N • 3 HBr, NBS, α-bromo-α,β-unsaturated carbonyl compounds, bromination, mild conditions

ID: J60-Y2009-2650