(2-Pyridyl)acetone-Promoted Cu-Catalyzed O-Arylation of Phenols with Aryl Iodides, Bromides, and Chlorides
Qi Zhang, Deping Wang, Xianyang Wang and Ke Ding*
*Key Laboratory of Regenerative Biology and Institute of
Chemical Biology, Guangzhou Institute of Biomedicine and Health, Guangzhou
Science Park, Guangzhou 510663, China, Email: ding_ke
gibh.ac.cn
Q. Zhang, D. Wang, X. Wang, K. Ding, J. Org. Chem., 2009, 74, 7187-7190.
DOI: 10.1021/jo9012157
Abstract
Copper-catalyzed coupling reactions of aryl chlorides, aryl bromides, and aryl iodides with various phenols successfully proceeded in good yields under mild conditions using (2-pyridyl)acetone as ligand. This reaction displays great functional groups compatibility and excellent selectivity.
see article for more examples
Key Words
ID: J42-Y2009-2750
