C-H Bond Activation: A Versatile Protocol for the Direct Arylation and Alkenylation of Oxazoles
François Besselièvre, Sabrina Lebrequier, Florence Mahuteau-Betzer, Sandrine Piguel*
*Univ Paris-Sud 11, 91405 Orsay, France, Email: sandrine.piguelcurie.u-psud.fr
F. Besselièvre, S. Lebrequier, F. Mahuteau-Betzer, S. Piguel, Synthesis, 2009, 3511-3512.
DOI: 10.1055/s-0029-1216987
Abstract
Pd(PPh3)4 efficiently catalyses both direct arylation and alkenylation of oxazoles. The method is regio- and stereospecific with respect to bromoalkenes and tolerates a wide range of functional groups.
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Key Words
oxazoles, arylation, alkenylation, palladium, C-H activation
ID: J66-Y2009-3050