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Access to α-Functionalized Glycine Derivatives with Arylboronic Acid via Imino Amides

Liang Zhao, Xiaohong Liao, Chao-Jun Li*

*Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 2K6, Canada, Email: cj.limcgill.ca

L. Zhao, X. Liao, C.-J. Li, Synlett, 2009, 2953-2956.

DOI: 10.1055/s-0029-1218266 (free Supporting Information)


Abstract

An efficient α-arylation of imino amides with arylboronic acids provides an alternative approach for the synthesis of α-functionalized glycine derivatives. Different substrates were examined for this arylation reaction.

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Key Words

α-arylation, iminol, imino amide, glycine derivatives


ID: J60-Y2009-3230