Platinum-Catalyzed Nucleophilic Addition of Vinylsilanes at the β-Position
Katsukiyo Miura*, Gen Inoue, Hisashi Sasagawa, Hidenori Kinoshita, Junji Ichikawa and Akira Hosomi
*Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University, Sakura-ku, Saitama 338-8570, Japan, Email: kmiuraapc.saitama-u.ac.jp
K. Miura, G. Inoue, H. Sasagawa, H. Kinoshita, J. Ichikawa, A. Hosomi, Org. Lett., 2009, 11, 5066-5069.
In the presence of catalytic amounts of PtCl2 and metal iodides, β-substituted vinylsilanes reacted with aldehydes at the β-position to give allyl silyl ethers. Addition to aromatic aldehydes proceeded efficiently in the presence of LiI whereas MnI2 was found to be effective in addition to aliphatic aldehydes.
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Allylic Alcohols, Silyl Ethers