Evolution of Efficient Strategies for Enone-Alkyne and Enal-Alkyne Reductive Couplings
Wei Li, Ananda Herath and John Montgomery*
*Department of Chemistry, 930 North University Avenue,
University of Michigan, Ann Arbor, Michigan 48109-1055, Email: jmontg
umich.edu
W. Li, A. Herath, J. Montgomery, J. Am. Chem. Soc., 2009, 131, 17024-17029.
DOI: 10.1021/ja9083607
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Abstract
Reductive coupling of enones or enals with alkynes using reducing agents such as organozincs, organoboranes, organosilanes, and methanol is cost-effective, and tolerant of many functional groups. Isotopic labeling strategies have provided supporting evidence for the mechanistic proposals.
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Catalytic Intermolecular Reductive Coupling of Enones and Alkynes
A. Herath, B. B. Thompson, J. Montgomery, J. Am. Chem. Soc., 2007, 129, 8712-8713.
Highly Chemoselective and Stereoselective Synthesis of Z-Enol Silanes
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Key Words
ID: J48-Y2009-3400
