Organocatalytic Stereoselective Aziridination of Imines via Ammonium Ylides
Lal Dhar S. Yadav*, Ritu Kapoor, Garima
*Green Synthesis Lab, Department of Chemistry, University of
Allahabad, Allahabad 211002, India, Email: ldsyadav
hotmail.com
L. D. S. Yadav, R. Kapoor, Garima, Synlett, 2009, 3123-3126.
DOI: 10.1055/s-0029-1218342
Abstract
The tertiary amine DABCO catalyzes the reaction of imines with phenacyl bromide derivatives to afford functionalized aziridines in high yields and stereoselectivities in a one-pot process - including the formation of ylides and their precursors.
see article for more examples
proposed mechanism
Key Words
aziridines, imines, nitrogen heterocycles, organocatalysis, stereoselective reaction, ylides
ID: J60-Y2009-3410
