An Expeditious Entry to Benzylic and Allylic Sulfones through Byproduct-Catalyzed Reaction of Alcohols with Sulfinyl Chlorides
Hai-Hua Li, De-Jun Dong, Yin-Huan Jin and Shi-Kai Tian*
*Department of Chemistry, University of Science and
Technology of China, Hefei, Anhui 230026, China, Email: tiansk
ustc.edu.cn
H.-H. Li, D.-J. Dong, Y.-H. Jin, S.-K. Tian, J. Org. Chem., 2009, 74, 9501-9504.
DOI: 10.1021/jo901974h
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Abstract
In the absence of external catalysts and additives, a broad range of benzylic and allylic alcohols react with various sulfinyl chlorides to afford structurally diversified benzylic and allylic sulfones in moderate to excellent yields. A catalysis with byproduct HCl is involved in this new protocol.
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Key Words
Benzylic Sulfones, Allylic Sulfones, Propargylic Sulfones
ID: J42-Y2009-3630
