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Iridium-Catalyzed, Regio- and Enantioselective Allylic Substitution with Aromatic and Aliphatic Sulfinates

Mitsuhiro Ueda and John F. Hartwig*

*Department of Chemistry, University of Illinois, 600 South Matthews Avenue, Urbana, Illinois 61801, Email: jhartwigillinois.edu

M. Ueda, J. F. Hartwig, Org. Lett., 2010, 12, 88-91.

DOI: 10.1021/ol9023248


Abstract

An iridium-catalyzed allylation of various sodium sulfinates with achiral allylic carbonates occurs in good yields, with high selectivity for the branched isomer, and high enantioselectivities (up to 98% ee).


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Key Words

Allyl Sulfones


ID: J54-Y2010-0130