Palladium-Catalyzed One-Pot Synthesis of 4-Aryl-1H-1,2,3-triazoles from anti-3-Aryl-2,3-dibromopropanoic Acids and Sodium Azide
Wensheng Zhang, Chunxiang Kuang*, Qing Yang
*Department of Chemistry, Tongji University, Siping Road 1239, Shanghai 200092, P. R. of China, Email: kuangcxtongji.edu.cn
W. Zhang, C. Kuang, Q. Yang, Synthesis, 2010, 283-287.
4-Aryl-1H-1,2,3-triazoles were synthesized from anti-3-aryl-2,3-dibromopropanoic acids and sodium azide by a one-pot method using N,N-dimethylformamide as solvent in the presence of Pd2(dba)3 and Xantphos.
see article for more examples
Y. Jiang, C. Kuang, Q. Yang, Synlett, 2009, 3163-3166.
Y. Jiang, C. Kuang, Q. Yang, Synthesis, 2010, 4256-4260.
1H-1,2,3-triazole, 1,2,3-triazoles, anti-3-aryl-2,3-dibromopropanoic acids, sodium azide, Pd2(dba)3, one-pot