Silicon Tetrachloride Catalyzed Aza-Michael Addition of Amines to Conjugated Alkenes under Solvent-Free Conditions
Najmedin Azizi*, Roya Baghi, Hossein Ghafuri, Mohammad Bolourtchian, Mohammad Hashemi
*Chemistry and Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran, Email: aziziccerci.ac.ir
N. Azizi, R. Baghi, H. Ghafuri, M. Boloutchian, M. Hashemi, Synlett, 2010, 379-382.
An efficient and very simple conjugate addition of aromatic and aliphatic amines to α,β-unsaturated carbonyl compounds under solvent-free conditions in the presence of catalytic amount of silicon tetrachloride gave the corresponding Michael adducts with very good yields.
see article for more examples
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N. Azizi, M. R. Saidi, Tetrahedron, 2004, 60, 383-387.