Oxidative Deamination of α-Aminophosphonates and Amines by Zinc Dichromate Trihydrate (ZnCr₂O₇ • 3 H₂O) under Solvent-Free Conditions at Room Temperature

Sara Sobhani*, Mahdi Faal Maleki

*Department of Chemistry, College of Sciences, Birjand University, Birjand 414, Iran, Email: ssobhanibirjand.ac.ir

S. Sobhani, M. F. Maleki, Synlett, 2010, 382-386.

DOI: 10.1055/s-0029-1219174

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Abstract

A rapid and efficient oxidative deamination of various α-aminophosphonates allows the synthesis of α-ketophosphonates using ZnCr₂O₇ • 3 H₂O under solvent-free conditions at room temperature. This method is also applicable to the rapid and highly selective oxidation of various amines to aldehydes and ketones in very good yields.

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Key Words

oxidative deamination, α-keto phosphonates, α-amino phosphonates, amines, ketones, aldehydes, chromium compounds

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ID: J60-Y2010-0300