Facile Preparation of 3-Substituted Benzisothiazoles from o-Mercaptoacylphenones
Nelmi O. Devarie-Baez and Ming Xian*
*Department of Chemistry, Washington State University,
Pullman, Washington 99164, Email: mxian
wsu.edu
N. O. Devarie-Baez, M. Xian, Org. Lett., 2010, 12, 752-754.
DOI: 10.1021/ol9028447
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Abstract
Starting from readily available o-mercaptoacylphenones, a mild S-nitrosation and a subsequent intramolecular aza-Wittig reaction lead to the construction of 3-substituted benzisothiazoles.
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proposed mechanism
Key Words
ID: J54-Y2010-0420
