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Tandem Ir-Catalyzed Allylic Substitution Reaction of Allyl Sulfinates and Isomerization

Qing-Long Xu, Li-Xin Dai and Shu-Li You*

*State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China, Email:

Q.-L. Xu, L.-X. Dai, S.-L. You, Org. Lett., 2010, 12, 800-803.

DOI: 10.1021/ol902873q (free Supporting Information)

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Using [Ir(COD)Cl]2 and a phosphoramidite ligand in the presence of DBU, trisubstituted vinyl sulfones could be synthesized from allyl sulfinates in high yields as exclusively E isomers.

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Key Words

Vinyl Sulfones

ID: J54-Y2010-0450