Iron(III)-Catalyzed Four-Component Coupling Reaction of 1,3-Dicarbonyl Compounds, Amines, Aldehydes, and Nitroalkanes: A Simple and Direct Synthesis of Functionalized Pyrroles
Sukhendu Maiti, Srijit Biswas and Umasish Jana*
*Department of Chemistry, Jadavpur University, Kolkata 700032, West Bengal, India, Email: jumasish2004yahoo.co.in
S. Maiti, S. Biswas, U. Jana, J. Org. Chem., 2010, 75, 1674-1683.
DOI: 10.1021/jo902661y (free Supporting Information)
see article for more reactions
An iron(III)-catalyed four-component coupling reactions of 1,3-dicarbonyl compounds, amines, aromatic aldehydes, and nitroalkanes without an inert atmosphere provides highly substituted pyrroles in good yields. Notably, this method is very cheap, straightforward, and environmentally friendly compared to existing methods.
see article for more examples