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K-10-Catalyzed Highly Diastereoselective Synthesis of Aziridines

Dmitry Borkin, Alena Carlson, Béla Török*

*Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd. Boston, MA 02125, USA, Email:

D. Borkin, A. Carlson, B. Török, Synlett, 2010, 745-748.

DOI: 10.1055/s-0029-1219361


Montmorillonite K-10 as solid acid catalyzes a stereoselective reaction of imines with ethyl diazoacetate to yield cis-aziridines. The reactions proceeded readily at room temperature in short reaction times, providing the products in very good yields and exclusive selectivity.

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Key Words

montmorillonite K-10, imines, aziridines, ethyl diazoacetate, heterogeneous catalysis, green chemistry

ID: J60-Y2010-0650