Direct Synthesis of Arylketones by Nickel-Catalyzed Addition of Arylboronic Acids to Nitriles
Ying-Chieh Wong, Kanniyappan Parthasarathy and Chien-Hong Cheng*
*Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan, Email: chchengmx.nthu.edu.tw
Y.-C. Wong, K. Parthasarathy, C.-H. Cheng, Org. Lett., 2010, 12, 1736-1739.
DOI: 10.1021/ol1003252 (free Supporting Information)
A convenient and efficient method allows the synthesis of various arylketones by nickel-catalyzed addition of arylboronic acids to nitriles. A catalytic cycle involving Ni(II) species as the catalytic intermediates is proposed.
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