Palladium-Catalyzed Asymmetric Addition of Diarylphosphines to Enones toward the Synthesis of Chiral Phosphines
Jian-Jun Feng, Xue-Feng Chen, Min Shi and Wei-Liang Duan*
*State Key Laboratory of Organometallic Chemistry, Shanghai
Institute of Organic Chemistry, Chinese Academy of Sciences, 345 LingLing Road,
Shanghai 200032, China, Email: wlduan
mail.sioc.ac.cn
J.-J. Feng, X.-F. Chen, M. Shi, W.-L. Duan, J. Am. Chem. Soc., 2010, 132, 5562-5563.
DOI: 10.1021/ja100606v
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Abstract
An asymmetric addition of diarylphosphines to β-substituted enones under mild conditions using a chiral pincer-palladium allows the synthesis of chiral phosphines with excellent enantioselectivity.
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Key Words
ID: J48-Y2010-1080
