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Highly Efficient Synthesis of Phenols by Copper-Catalyzed Oxidative Hydroxylation of Arylboronic Acids at Room Temperature in Water

Jimin Xu, Xinyan Wang*, Changwei Shao, Deyong Su, Guolin Cheng and Yuefei Hu*

*Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China, Email: wangxinyanmail.tsinghua.edu.cn, yfhmail.tsinghua.edu.cn

J. Xu, X. Wang, C. Shao, D. Su, G. Cheng, Y. Hu, Org. Lett., 2010, 12, 1964-1967.

DOI: 10.1021/ol1003884


Abstract

A general and efficient copper-catalyzed oxidative hydroxylation of arylboronic acids at room temperature in water gives phenols in excellent yields.

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Key Words

phenols, green chemistry


ID: J54-Y2010-1220