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Ecofriendly Iodination of Activated Aromatics and Coumarins Using Potassium Iodide and Ammonium Peroxodisulfate

Nemai C. Ganguly*, Sujoy Kumar Barik, Sanjoy Dutta

*Department of Chemistry, University of Kalyani, Kalyani 741235, WB, India, Email:

N. C. Ganguly, S. K. Barik, S. Dutta, Synthesis, 2010, 1467-1472.

DOI: 10.1055/s-0029-1218698


An environmentally benign protocol for the iodination of activated aromatics, such as phenols, anilines, and hydroxycoumarins, using inexpensive commercially available potassium iodide and ammonium peroxodisulfate in aqueous methanol at room temperature provides predominantly ortho-monoiodinated products. This acid-free method is compatible with various oxidizable functional groups.

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Key Words

iodination, potassium iodide, ammonium peroxodisulfate, activated aromatics, coumarins, green chemistry

ID: J66-Y2010-1230