Mild Conditions for Copper-Catalyzed N-Arylation of Imidazoles
Huaming Chen, Deping Wang, Xianyang Wang, Wenlong Huang, Qian Cai, Ke Ding*
*Key Laboratory of Regenerative Biology and Institute of
Chemical Biology, Guangzhou Institutes of Biomedicine and Health, Chinese
Academy of Sciences, Guangzhou International Business Incubator D-10, Guangzhou
Science Park, Guangzhou 510663, P. R. of China, Email: ding_ke
gibh.ac.cn
H. Chen, D. Wang, X. Wang, W. Huang, Q. Cai, K. Ding, Synthesis, 2010, 1505-1511.
DOI: 10.1055/s-0029-1218691
Abstract
An efficient copper(I) bromide catalyzed N-arylation of azoles with a variety of aromatic bromides and iodides under mild conditions displayed great functional group compatibility and excellent reactive selectivity.
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Key Words
copper, aryl halides, imidazoles, azoles, N-arylation
ID: J66-Y2010-1300
