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Nickel-Catalyzed Allylic Substitution of Simple Alkenes

Ryosuke Matsubara and Timothy F. Jamison*

*Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Email: tfjmit.edu

R. Matsubara, T. F. Jamison, J. Am. Chem. Soc., 2010, 132, 6880-6881.

DOI: 10.1021/ja101186p (free Supporting Information)


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Abstract

A nickel-catalyzed intermolecular process for direct allylation of nonconjugated, nonstrained simple alkenes affords the desired linear 1,4-dienes in high yield in both gram-scale and smaller scale coupling reactions.

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Key Words

1,4-dienes


ID: J48-Y2010-1420